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Therefore, it is important to balance the benefits and risks of these drugs and closely monitor patients during treatment

Despite its beneficial roles, excessive production of NO can lead to its reaction with superoxide to form peroxynitrite (ONOO ), a potent oxidizing and nitrating agent [31]
Severe consequences like diminished absorption of nutrients, synthesis of vitamins and non-essential amino acids, and accelerated risk of obesity, asthma, diabetes, and infections

Trends Microbiol 2001
Rana S, Dringen R
