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Perhaps the best characterized endogenous conjugated OA substrates of MRP1 are the earlier mentioned GSH and glucuronide conjugates, LTC 4 and E 2 17G, respectively (4, 17, 62, 63)

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However, even with the support of evidence-based medicine and extensive applications in a clinical setting, first-line medications for osteoporosis still fall short in terms of patient adherence, gaps in drug efficacy compared to trial outcomes, side effects, drug selection, and personalized treatment (33)

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Deragon MA, McCaig WD, Patel PS, Haluska RJ, Hodges AL, Sosunov SA, et al

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Tumor progression can be influenced by metabolism, including antioxidant glutathione (GSH)

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EFSA J 21:e07704 Nayak V, Singh KRB, Singh AK, Singh RP (2021) Potentialities of selenium nanoparticles in biomedical science

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