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[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Cole T.B., Wenzel H.J., Kafer K.E., Schwartzkroin P.A., Palmiter R.D

Chronic treatment with PARP inhibitors increased NAD + levels and mitochondrial respiration in 10-week-old mice and triggered UPR mt and increased mitochondrial respiration and lifespan in worms 109,257

Furthermore, when antigen presenting cells have high intracellular GSH levels they secrete cytokines that favor the development of Th1 cells [81]

It is astonishing that notwithstanding the Tietzes method for glutathione titration is the most cited one in the literature (4111 hits on Scopus database) and most of the commercially available kits are still based on its procedure, his findings and warnings on GSSG values have been rapidly and are still consistently ignored

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