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As shown in Table 1 and Figure 6, in the pursuit of structurally diverse NNMT inhibitors, researchers have identified certain macrocyclic peptides that bind to NNMT, displaying potent inhibition with Half-maximal inhibitory concentration (IC 50 ) values as low as 229 nM (Van Haren et al., 2021)

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Glucosamine assists the body in providing components necessary to synthesise proteoglycans, which are required for articular cartilage synthesis [5]

However, studies show that 1.5-6 g per day, divided into 2-3 doses, is beneficial and safe for patients with osteoarthritis

Figure 5: The technological process of extraction of glutathione from yeast cell Uses 1.Reduced glutathione is a kind of small molecular peptide, a large number of peptides in living organisms, especially in liver cells, protect the liver cell membrane, promote the role of liver enzyme activity, and with a number of toxic chemicals in combination with play the role of detoxification