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Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007

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IV therapy can support hydration and nutrient delivery during a nurse-delivered visit, while take-home kits may support consistency between appointments when a clinician has reviewed your health history and approved the plan

doi:10.1002/jimd.12009

"But we were quite surprised that it was the number was as high as it was." Silverstein and his colleagues calculated the inappropriately prescribed shots needlessly cost the province's health-care system $45.6 million annually
