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These reactive compounds interact with amino groups (NH 2 ) in proteins and DNA bases, leading to the formation of adducts that can cause mutations (Yang et al., 2019)
doi:10.4067/s0034-98872017000700907
The pain usually affects the lower extremities first and extends upward through hosiery-like sensory abnormalities [81, 82]
102(37): e34959
Cancer Cell 17 , 98110 (2010)
