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Mechanisms of miRNA-mediated SIRT1 regulation in liver cancer Nakano and colleagues found that when miR-4669 is overexpressed in HCC cells, it enhances their migration ability and leads to the development of resistance to sorafenib, a commonly used drug for HCC treatment

For example, Borneolum Syntheticum increases vascular permeability and modulates membrane transport to enhance drug distribution [200]

2021;53:e13624

Alpha-1 antitrypsin inhibits ATP-mediated release of interleukin-1beta via CD36 and nicotinic acetylcholine receptors

And among these manganese- based nanomaterials, manganese dioxide nanoparticles (MnO 2 NPs) are one of the most stable and functional nanomaterials with some important biological activities and immunological response regulatory activities (5)