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Composed of an N-terminal signal peptide, an N-terminal coiled-coil domain, a linker region and a C-terminal fibrinogen-like domain, it shares high sequence homology with both ANGPTL4 and ANGPTL8 [5]

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10.1176/jnp.15.3.317 [DOI] [PubMed] [Google Scholar] Ojaniemi M., Glumoff V., Harju K., Liljeroos M., Vuori K., Hallman M

Non-hormonal causes should be considered and adequate diagnostic measures taken to rule out malignancy or pregnancy in the event of breakthrough bleeding, as in the case of any abnormal vaginal bleeding