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However, it increased heart rate, cardiac output, and induced myocardial degeneration in mice and thus was terminated as a preclinical candidate (Yau et al., 2017)

While it is available as a dietary supplement and has shown positive results in animal studies, clinical trials have yet to investigate its efficacy and safety in various applications

10.1002/mnfr.202300286 12 BudnowskiJ.HanskeL.SchumacherF.GlattH.PlatzS.RohnS.et al (2015)

The same latent variables of perceived sleep quality, sleep efficiency and daily disturbances were the factor loading for the three-factor model
