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Tirzepatide: The dual-agonist (GLP-1/GIP) current market gold standard

adding GIP agonism appears to further enhance the appetite and metabolic effect

Mood Instability and Emotional Dysregulation: The restoration of neurotransmitter synthesis via the methylation cycle also directly impacts emotional well-being

Raj S, Kesari KK, Kumar A, Rathi B, Sharma A, Gupta PK, Jha SK, Jha NK, Slama P, Roychoudhury S, Kumar D

Damage to the tubular endothelial cells can increase leukocyte adhesion, platelet aggregation, and vasoconstriction, reduce blood flow to nephrons, and damage the glomerular barrier and the extensive network of peritubular capillaries (88)
