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In addition to MNAM and NNMTi, three new NAM analog inhibitors were reported for the treatment of MetS-related disorders in animal models: JBSNF-000088 ( JBSNF-000265 (Ruf et al., 2018), and JBSNF-000028 (Ruf et al., 2022)

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NEOVA's formulations are pH-optimized to maintain peptide stability and tolerability