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Under the stimulation of high mechanical stress, activation of the PIEZO1 protein leads to a decrease in the intracellular GSH level of chondrocytes, a reduction in the function and expression of GPX4, and a significant increase in the intracellular calcium ion concentration, ultimately inducing ferroptosis of chondrocytes
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10.1017/S0029665199000580 38 SelhubJ.MorrisM
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[PubMed] [Google Scholar] 194.Noguera-Mazon V
