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Kidney function highly depends of the homeostasis of this organelle, and mitochondria play a hub in signaling pathways, metabolic regulation, calcium homeostasis, and inflammation through the redox regulation, which also is important for the feedback communication with other organelles like endoplasmic reticulum (ER) and peroxisomes (MartnezKlimova et al
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IL-6 exhibits a protective role in the early phase while causing pathology in the chronic phase of TB infection, thereby stating it to be controversial (Zhang et al., 1994)
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