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The peptide remains experimental, unapproved, and controversial

You can endoscopically see Intestinal Metaplasia (IM), but there may be an advanced grade of Barretts in an area that was not sampled

At least 1 in 4 people develop aphthous mouth ulcers at some stage in their lives

This routes limitation is related to the small dose that can be administered, which implies the need to design and formulate a drug with a high loading capacity [16], making the route effective only for very potent drugs [6]

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