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Description

[1] This reaction is easily reversible, and does not require any energy input, as both fatty acyl-CoAs and fatty acylcarnitines are considered chemically activated forms of fatty acyl groups

Acid-labile linkers are designed to be stable at pH levels encountered in the blood, but become unstable and degrade when the low pH environment in lysosomes is encountered

Authors' Contributions Soheila Montazersaheb and Raheleh Farahzadi contributed mainly to design and manuscript writing

Mechanism of Action Sermorelin exerts its effects through high-affinity binding to and activation of growth hormone-releasing hormone receptors (GHRHR) expressed on somatotroph cells in the anterior pituitary gland