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El-Saadony and colleagues (2023), turmeric is no longer viewed merely as a simple culinary ingredient

NNMT sits between NAD+ metabolism and one-carbon methylation metabolism, pathways that support redox reactions, DNA repair, and transcriptional regulation

JBSNF-000088 binds to the active site on NNMT and leads to the demethylation of SAM to SAH ( JBSNF-000028 (Ruf et al., 2022) and JBSNF-000088 ( JBSNF-000265 was discovered through Structure-Activity Relationship (SAR) studies (Ruf et al., 2018) as a compound that binds to NNMT in a manner similar to that of NAM

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BPC-157 is not approved by the FDA or veterinary regulatory agencies for use in animals
