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Although significantly higher than those of PBS treated mice, GGsTop greatly inhibited the increased levels of eosinophils in bone marrow and peripheral blood of OVA/LPS/GGsTop treated animals, suggesting that this inhibitor has systemic effect on eosinophilic inflammation during asthma exacerbations

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18 Amantadine, a blocker of N-methyl-D-aspartate glutamate receptors, had a modest effect in symptom reduction, 19 but the evidence supporting its use was scant, making it a consideration only when other established treatments were not viable

Srheim et al., 2010)