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First, a rapid decline in serum urate levels may disrupt pre-existing crystaldissolution equilibria, leading to structural rearrangement of deposited MSU crystals, exposure of previously concealed crystal surfaces, or mobilization of microcrystalline particles
doi:10.1016/j.nut.2012.08.012
Hu G, Qiao Q, Tuomilehto J, Balkau B, Borch-Johnsen K, Pyorala K
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