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Mitochondria-targeted liposomes induce massive lipid peroxidation and increase ROS in mitochondria, ultimately triggering ferroptosis in bladder cancer cells, promoting the release of intracellular DAMPs, inducing the release of mtDNA into the cytoplasm, activating the cGAS-STING pathway to secrete IFN-, and increasing DC cross-presentation of antigens to T cells, and increasing macrophage phagocytosis (250)

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Macrocircuit dysfunction and redox dysregulation in relation to disrupted myelination and white matter integrity diffusion properties In addition to PV neurons, oligodendrocytes are highly sensitive to altered redox state [155]

PMID: 240 SylvesterFA

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