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salivarius cells under acid stress [40]

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SIM images were taken on a Zeiss Elyra PS.1 microscope with Plan-Apochromat 63/1.4 Oil differential interference contrast (DIC) M27 objective

It is unlikely that this phenomenon was due to the contaminants of street heroin, or to factors such as age, renal function, and route of administration, which are known to affect morphine metabolism [61, 62]