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Richardson SM, Walker RV, Parker S, Rhodes NP, Hunt JA, Freemont AJ, et al

Takeshima M, et al

Wilhelm RC, DeRito CM, Shapleigh JP, Madsen EL, Buckley DH

Steps to check your coverage before ordering through a lab: Ask your physician whether your clinical situation qualifies as a covered indication Call your insurer and ask specifically about CPT code 81291 (MTHFR Mutation Analysis) Request a prior authorization if required by your plan before the test is ordered Confirm the lab is in-network LabCorp and Quest are widely covered but verify with your specific plan Direct-to-consumer at-home tests like PlexusDx are not covered by standard health insurance regardless of indication

Valenti D, Braidy N, De Rasmo D, Signorile A, Rossi L, Georgiev Atanasov A, et al