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The overexpression of WT PINK1 has been shown to down-regulate TH expression and DA level to protect human dopaminergic neurons [42]
Regulation PPP activity correlates with NADPH demand (Fig
Inflammation in the predia- betic state is related to increased insulin resist ance rather than decreased insulin secretion
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Deficiency of this protein (about 1 in 4000 worldwide) is commonly associated with emphysema, progressive lung disease, and also hepatic damage resulting from accumulation of protein aggregates
