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Overall, increased oxygen consumption, energy production, and lactic acid production during high-intensity exercise can increase free radicals and oxidative stress, which can cause damage to cells and tissues if not adequately neutralized by the bodys antioxidant defense system

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The Role of Elemental Selenium in Selenoproteins The most unique feature of the mammalian GPX family is that many of them, apart from GPX-5, GPX-7, GPX-8, and GPX-6 in rodents, are selenoproteins [13]