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For these six subjects, baseline GSH levels were all assigned the same value (the lowest measured GSH/Cr ratio value across all subjects and scans, divided by 2), in order to calculate the absolute change in GSH/Cr ratio relative to baseline

Thirty-one patients with cerebral microangiopathy were included for comparison

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Also, melatonin receptors are transiently expressed in neuroendocrine tissues during development, suggesting that melatonin has a role as a neuroendocrine synchronizer in developmental physiology (44)