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b) Protect from sunlight

16 Although transcription and translation are intimately associated in bacteria in space and time, there are other factors that can alter the final amount of protein and, subsequently, the final function trusted in those proteins

Given the lack of efficacy in an in vivo model, we decided to evaluate the effects of Molidustat in a more relevant system where drug delivery could be better controlled

[DOI] [PubMed] [Google Scholar] 98.Khan S.K., Malinski T., Mason R.P., Kubant R., Jacob R.F., Fujioka K., Denstaedt S.J., King T.J., Jackson H.L., Hieber A.D., et al

Given the observed increase in ROS, we tested whether pharmacological inhibition of GSTP1 could recapitulate the Molidustat-induced apoptosis in PHD2 knockout cells using Ezatiostat