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doi: 10.1021/acs.chemrestox.9b00478

For instance, daily administration of antioxidant grape seed proanthocyanidin extract at Zeitgeber time 0 (ZT0) can restore the disrupted diurnal rhythms of catalytic activity, GPX1 activity, and GSH levels in rats subjected to a cafeteria diet, whereas treatment at ZT12 fails to achieve this effect [278]

This interaction lowers the vulnerability of liver cancer cells to ferroptosis and reduces the induction of ferroptosis (64,89,90)

Young Cho Y, Jeong Kim H, Won Jang H, et al

Single-cell RNA sequencing (scRNA-seq) of human colonic biopsies identified distinct clusters of fibroblasts involved in crypt architecture by expressing genes essential for stem cell functionality [39, 40]