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Graphical Abstract Similar content being viewed by others Introduction Ulcerative colitis (UC), characterized by chronic intestinal inflammation and epithelial barrier dysfunction, remains a therapeutic challenge due to its complex etiology involving dysregulated immune responses, microbiota dysbiosis, and aberrant cell death pathways [1, 2]

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Lyophilized peptides are extremely light and potent

However, its mechanisms of occurrence and development in pain still need further study in the future