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Similar studies have demonstrated NRF2 KO mice have increased susceptibility to autoimmune conditions such as lupus nephritis [28] as well as pulmonary [29] and cardiovascular disease [30]

International Journal of Cosmetic Science 27(3):155-160. [doi.org]

NSUN2 promotes colorectal cancer progression by stabilizing PHGDH mRNA to promote serine metabolism reprogramming

I dont see their incentive to lie, especially since most turn to public forms for help, so I am inclined to believe that there is a small minority of people who dont react well to topical copper

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