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Oxidative stress can also be caused by the mitochondrial localization of viral proteins

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Methylsulfonylmethane, commonly known as MSM, is a naturally occurring and essential compound found in humans, as well as in green plants and animals, playing a vital role in supporting overall health and vitality

1 Introduction Ferroptosis is a non-apoptotic form of regulated cell death driven by iron-dependent membrane lipid peroxidation, which compromises plasma membrane permeability and integrity, ultimately leading to membrane rupture and cell death ( Though ferroptosis is a relatively newly discovered form of regulated cell death, ferroptosis has gained considerable attention, and increasing evidence suggested that it plays a critical role in various diseases, including cancer, neurodegenerative diseases, and tissue ischemia injury ( 2 Mechanisms of ferroptosis Mechanistically, cellular lipid peroxidation occurs in three key steps: (1) Initiation, where reactive oxygen species (ROS) abstract a hydrogen atom from PUFAs-containing membrane phospholipids, generating lipid radicals (L )

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