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Mechanism of action and actions on the CNS Valproic acid exerts its pharmacological action in several ways, including increasing levels of GABA ( aminobutyric acid) in the CNS, suppressing histone deacetylase, and blocking voltage-gated ion channels

Therapeutic effects in patient-derived osteosarcoma xenograft mouse model For a better understanding of the clinical potential, its therapeutic properties were assessed in a patient-derived osteosarcoma xenograft mouse model (PDX OS ) in immunodeficient nude mice (protocol for model establishment: Fig

Aluminum as a toxicant

[DOI] [PubMed] [Google Scholar] Evans W.J., Morley J.E., Argils J., Bales C., Baracos V., Guttridge D., Jatoi A., Kalantar-Zadeh K., Lochs H., Mantovani G., Marks D., Mitch W.E., Muscaritoli M., Najand A., Ponikowski P., Rossi Fanelli F., Schambelan M., Schols A., Schuster M., Thomas D., Wolfe R., Anker S.D

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