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Marine SCPs and aminosterols have a specific stereochemistry and post-translational modifications that are important for their biological activity, which are challenging to replicate in laboratory-engineered technologies


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In summary, these results further support the hypothesis that IFN signaling can promote RMC tumor cell state changes, prompting further investigation into the pharmacological inhibition of myeloid-affiliated mediator, p300, which is downstream of IFNGR1
