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A later study using lineage-specific fluorescent reporters did not support tumor cells as a source of endothelial cells in glioma, instead demonstrating that glioma cancer stem cells can differentiate into pericytes and that specific depletion of pericytes disrupted tumor vessels and tumor growth [81]

For each experiment, the mean fluorescence and size were calculated in each bin, and normalized to the median of the respective experiment

1l), predictive of extended plasma half-life 29

Several important safety considerations warrant attention

Paul, MN, USA) proprietary Biosystem XA software (version 2.9.0.2) and proprietary FinePointe software (version v2.8.0), as described previously 87,88,89,90,91,92,93,94,95,96,97 and as detailed in the Data Sciences International/Buxco website reference to the list of parameters provided by FinePointe Software using whole body plethysmography ( The BioSystem XA software extracts the waveforms that are analyzed by the FinePointe software that uses National Instruments Measurement Studio to perform these analyses ( Righting reflex Separate groups of adult male SpragueDawley rats were used to evaluate the effects of GSHee (100 mol/kg, IV) on the duration of fentanyl (75 g/kg, IV)-induced impairment of the righting reflex (inability to stand on all four legs)