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In cancer, the same H 2 O 2 signals that sustain growth and EMT coexist with antioxidant rewiring, creating a therapeutic window where node- and compartment-specific interventions (NOX/NOS modulation, mitochondrial quality control, iron/ferroptosis management, calibrated RSS support) outperform blanket scavenging (Lankheet et al

Monoamine oxidases: to inhibit or not to inhibit

Interestingly, the acidification of the microenvironment caused by secreted lactate is believed to promote invasion 70

Glutamic acid sodium salt can be used to study neurotoxicity (e.g., brain damage, cognitive impairment), metabolic disorders (e.g., obesity, insulin resistance), hepatotoxicity, and renal toxicity, as well as pain-related disorders

[Google Scholar] 11.DAiuto F, Nibali L, Parkar M, Patel K, Suvan J, Donos N