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The superior redox properties of Se are a likely explanation for why Se is essential to selenoproteins despite its incorporation challenges

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Think about the effort that goes into creating a research-grade peptide

Parenteral administration of minute amounts of endotoxins to humans elicits an inflammatory reaction typical of SIRS (fever or hypothermia, tachycardia, hyperpnea, leukocytosis, and hypotension), whereas larger amounts of administered endotoxins typically produce sepsis and shock [66, 67]

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