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Furthermore, suppression of IGF-1R activity has been proven to enhance radiosensitivity in cancer due to delayed double-strand break repair in cancer cells [41]

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Induced pluripotent stem cells (iPSC)-derived oligodendrocytes from these patients also showed more accumulation of VLCFAs when compared to the AMN patients [24]

In one series of 41 patients with childhood onset adenomas, 29 (70%) were prolactinomas, 5 (12%) were ACTH secreting adenomas, one patient (2%) presented with a GH secreting adenoma and the remaining 6 patients (15%) presented with non-functioning adenomas (198)

This abundance of selenium-laden residues strongly implies a pivotal function in the transport and distribution of selenium throughout the body, underscoring the unique biological role of SelP in selenium transport