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[DOI] [PubMed] [Google Scholar] 118.Berdenis van Berlekom A, Muflihah CH, Snijders GJLJ, MacGillavry HD, Middeldorp J, Hol EM, et al

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations EPO: erythropoietin HIF: hypoxia-inducible factor ODDD: oxygen-dependent degradation domain pVHL: von HippelLindau tumor suppressor protein References Semenza GL, Wang GL

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Furthermore, by using BSO a chemical inhibitor of glutamate cysteine ligase (GCL), an enzyme responsible for glutathione synthesis we depleted glutathione levels in A549 cells and observed significant increase in sensitivity to cisplatin, confirming the importance of glutathione in determining cisplatin resistance