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TMAO (or trimethylamine N-oxide) is a metabolite produced by gut bacteria

Overall, the data favor a role for diets rich in long-chain omega-3 fatty acids in slowing cognitive decline, but larger trials with longer intervention periods may be necessary to see a consistent beneficial effect of omega-3 supplementation in older individuals with normal or declining cognitive functions

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The synthetic pathway encompasses numerous enzyme-mediated transformations, including a crucial reaction catalyzed by -butyrobetaine hydroxylase (-BBH)

Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis