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Through upregulating the mRNA levels of germ cell specific genes (e.g., DAZL, VASA, and PIWIL2), as well as meiotic genes (e.g., SCP3, Cyclin A1, and STRA8), HAM MSCs could increase protein expressions of survivin and Bcl-2, while reducing those of Capase3 and Capase9, thereby enhancing the anti-apoptotic ability of testicular tissue cells in mice, thus treating busulfan-induced damage to testicular tissues in mice (100)

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Thorax 41 , 903913 (1986)

A.KobeB.et al (2013)

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