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PPP-produced NADPH is considered to be crucial in the defence against oxidative stress, which is often induced by exogenous sources or disrupted mitochondrial activity 26
Cancer 19 , 91 (2020)
Semidehydroascorbate is reconverted to ascorbate in the cytosol by cytochrome b 5 reductase and thioredoxin reductase in reactions involving NADH and NADPH, respectively
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(PubMed) Raza S, Rajak S, Upadhyay A, Tewari A, Anthony Sinha R
