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Additionally, a 7-year prospective study found that while NSW alone was not significantly associated with chronic pain or CRP levels, the combination of NSW and moderately elevated CRP was associated with an increased risk of chronic pain and pro-inflammatory background 150

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a , b , Representative 5 m maximum projections in the xz plane ( a , b ) or 25 m projections in the xy plane ( b ) were captured from CX3CR1 gfp/+ mice at 60 min ( a ) or 6 h ( b ) after a normal thinned skull preparation (uncompressed) or compression injury

Weidner KM, Behrens J, Vandekerckhove J, Birchmeier W

Mast cells, a type of granulocyte, contain chemicals needed in the bodys immune response