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& Macias, M
Depletion of intracellular glutathione (GSH) markedly promotes mitochondrial ROS production and triggers mitochondrial membrane depolarization (Lohan et al., 2018)
For more detailed information on the normal biological function of HCA 2 go to the Bioactive Lipids and Lipid Sensing Receptors page
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This decline contributes to mitochondrial dysfunction, oxidative stress , and the increased likelihood of developing age-related diseases
