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COPD airway epithelial cells have greater initial concentrations of IL-8, which effectively causes mucous hypersensitivity by expressing the mucosal genes MUC5B and MUC5AC [219]

More recently Thompson's research group studied mice that were injected with human breast cancer cells

The heroin-dependent mouse model had reduced gut microbial alpha diversity with higher levels of Bifidobacterium and Sutterella and reduced levels of Akkermansia compared to controls (201)

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[DOI] [PubMed] [Google Scholar] (127).Smith-Gonnell J
