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In fact, because the RFC pathway is less efficient, studies use high doses of leucovorin to ensure enough folate reaches the brain

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These include vitamin C, which helps to brighten the skin tone, and vitamin E, which helps to protect the skin from damage

In addition, previous research revealed that loss of leukemia inhibitory factor receptor (LIFR) promoted liver tumorigenesis and conferred resistance to drug-induced ferroptosis

Considering such factors, Yang and the team assessed the effect of cetuximab in combination with RSL3 on viability of KRAS mutant CRC cells