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doi: 10.3389/fonc.2025.1700439 Received 11 September 2025 Accepted 27 October 2025 Published 17 November 2025 Volume 15 - 2025 Edited by Zodwa Dlamini, Pan African Cancer Research Institute (PACRI), South Africa Reviewed by Yuan Qin, Xijing Hospital, The Air Force Medical University, China Hong Sun, Fudan University, China Updates Copyright 2025 Ao, Liu, Yin and Zhao

This is particularly true for those with higher skin phototypes who may not normally wear sunscreen, but also may not realize the darkening effects UV irradiation has on hyperpigmentation

Ma, N., Li, Y., Xu, H., Wang, Z

Another significant study highlighted that ASN90 (also referred to as ASN-120290 or ASN-561), a novel OGA inhibitor, improved survival, respiratory function, and motor skills in the JNPL3/P301L mouse model of AD, attributed to an increase in O-GlcNAcylated Tau and a reduction in neurofibrillary tangles [183]

Other than incorporation into protein, the most important metabolic functions of cysteine are in the synthesis of glutathione (GSH), the synthesis of the bile salt modifying compound, taurine, and as a source of the sulfur for coenzyme-A synthesis