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However, these safety data come from systemic administration studies

This paradigm is obviously particularly important, as it prevents the rapid release of a large amount of substance into the bloodstream with the detrimental consequences already mentioned, but it is equally important to develop formulations that enable the controlled release of the active ingredient from these deposits as a way to extend the duration of the expected effect

doi: 10.1074/jbc.M105102200 38 Vanden BergheTvan LooGSaelensXVan GurpMBrouckaertGKalaiMet al
N -acetylcysteine NAC has gained recognition for its potential role in the management of UTIs, particularly in the context of recurrent UTIs

Polyphenols in the mediterranean diet: from dietary sources to MicroRNA modulation