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However, these phase-dependent shifts influence nutrient metabolism indirectly by reshaping insulin sensitivity, gastrointestinal function, and reproductive axis signaling, and by modulating motivational states that govern food intake and dietary choice [60,61,62,63]

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However, a significantly higher 8-OHdG plasma concentration was observed in the migraine patients as compared with the control, as well as in the group of patients with migraine without aura in comparison with the group of patients with migraine with aura [33]

Virus-hijacked host cellular factors Clinical outcomes of COVID-19 are directly related to the ability of the SARS-CoV-2 pathogen to hijack host metabolic machinery as well as cellular factors of an infected individual, for viral invasion and internalization, followed by intra-cellular replication to assemble and release multiple viral copies for ultimate propagation/transmission