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We generated stable knockout HT-29 cell lines using CRISPR-Cas9 with guide RNAs targeting STK38 (Fig

When patients present with concerning symptoms whilst taking B12 supplements, alternative diagnoses should be considered, including allergic reactions to supplement excipients, interactions with other medications, or coincidental illness

Nomenclature of targets and ligands Key protein targets and ligands in this article are hyperlinked to corresponding entries in the common portal for data from the IUPHAR/BPS Guide to PHARMACOLOGY (Harding et al ., 2018), and are permanently archived in the Concise Guide to PHARMACOLOGY 2017/18 (Alexander et al ., 2017a,b,c,d)

Initial interest in the use of metformin for preventing and treating lung cancer arose from a number of clinical studies suggesting that metformin reduces the risk of lung cancer in individuals with diabetes (3941)

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