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In addition, gliotoxin can also induce apoptosis via the deregulation of NOTCH2 mRNA expression towards cell lines derived from melanoma (518A2), hepatocellular carcinoma (SNU398, HCC-3, Hep3B), and pancreas carcinoma (PANC1) with the high expression level of NOTCH 2
Nianiou-Obeidat et al., 2017)

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doi: 10.1016/S0002-9440(10)63645-0