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d , U2OS cells stably expressing mCherryPDIA6 were treated with A23187

or another CNS disorders, such as primary brain tumors, epilepsy/seizures, migraine and other headaches (cluster, vascular, tension), narcolepsy, insomnia (and other sleep disorders), chronic fatigue syndrome, mountain sickness, obesitas, bacterial and viral encephalitis, bacterial and viral meningitis, AIDS-related dementia

Similarly, the down-regulation of miR-27a (oncogenic) but the upregulation of miR-34a were induced by curcumin accompanied by modulation of downstream targets, leading to cell cycle arrest and apoptosis in colorectal cancer cells (Toden et al., 2015)

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Thymosin B4: A potential molecular target for tumor therapy