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The dosing framework comes from extrapolation: murine studies scaled by body surface area, in vitro keratinocyte studies reverse-engineered to estimate required serum concentration, and anecdotal protocols from research communities using off-label peptides
(November 2023)
This group also reported that low maternal vitamin B-12 plasma concentrations in pregnancy were correlated with insulin resistance, as measured by the HOMA-IR in children aged 6 y (39)
The results of a 2005 study, for instance, showed that eliminating Methionine in the diets of mice extended life
Yes, older patients might need special treatment plans
